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Renal insufficiency induced by cisplatin in rats is ameliorated by cyclosporin A

โœ Scribed by Philip I. Campbell; Ibrahim A. Al-Nasser

Book ID
118578874
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
627 KB
Volume
114
Category
Article
ISSN
0300-483X

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## Abstract The aim of this study was to investigate the optimum dosage of erdosteine to ameliorate cisplatinโ€induced nephrotoxicity. Three different doses of erdosteine at 25, 50 and 75 mg kg^โˆ’1^ were studied in rats. Intraperitoneal administration of 7 mg kg^โˆ’1^ cisplatin led to acute renal failu