Renal handling of phosphate, calcium, sodium, and potassium in intact and parathyroidectomizedRana pipiens

✍ Scribed by Sasayama, Yuichi ;Clark, Nancy B.

• Publisher: John Wiley and Sons
• Year: 1984
• Tongue: English
• Weight: 601 KB
• Volume: 229
• Category: Article
• ISSN: 0022-104X
• DOI: 10.1002/jez.1402290204

✦ Synopsis

Renal excretion of phosphate, calcium, sodium, and potassium in intact and parathyroidectomized male Rana pipiens was studied by renal clearance techniques using l4C-inulin. In intact frogs, 57% of filtered phosphate, 60% of filtered calcium, 97% of filtered sodium, and 89% of filtered potassium was reabsorbed by the renal tubules. Following parathyroidectomy, the rate of reabsorption of phosphate became significantly higher than that of the intact frog, and the relative phosphate clearance (fractional excretion) decreased. These changes corresponded with a gradual rise in serum phosphate values. There was no major effect on excretion patterns of calcium, sodium, or potassium after parathyroidectomy. These results suggest that in frogs the parathyroid glands strongly influence phosphate excretion patterns but have little effect on the excretion of calcium, sodium, or potassium.