Renal function in the harbor seal (Phoca Vitulina L.) during asphyxial ischemia and pyrogenic hyperemia

✍ Scribed by Bradley, Stanley E. ;Bing, R. J.

• Publisher: Wiley (John Wiley & Sons)
• Year: 1942
• Tongue: English
• Weight: 466 KB
• Volume: 19
• Category: Article
• ISSN: 0095-9898
• DOI: 10.1002/jcp.1030190211

✦ Synopsis

and the Depnrtments of Medicine and Physiology, S c w Fork. University College of Medin'ne THREE FIGURES

Irving aiicl his collaborators (Irving, '39 ; Irving, et al., '42) have demonstrated that the seal, like other diving mammals, can survive long periods of asphyxia during diving by a coordinated mechanism which involres respiratory inhibition and maintenance of arterial blood pressure, accompanied by a marked bradycardia. I n another niammalian diver, the beaver, there occurs a decrease in flow of blood t o muscles and an increase in flow through the brain during asphyxia (Irving, '38). I n this animal the vasoconstrictor response is apparently independent of breathing movenients, vagal activity, o r carotid and aortic pressor receptors. The above physiological adjustments probably reclnce the total oxygen consumption of the oiiiinal during apnoea, while assuring adequate delivery of oxygen to the brain and heart.

'Aided by n grant from the Edward PIT. Giblis Prizc Fund of the P;ew York Academy ' Commoiiwealth Fund Fellow.