Renal fluoride excretion as a useful parameter for monitoring hydrofluoric acid-exposed persons
✍ Scribed by A. Zober; M. Geldmacher v. Mallinckrodt; K. H. Schaller
- Book ID
- 104772065
- Publisher
- Springer-Verlag
- Year
- 1977
- Tongue
- English
- Weight
- 564 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0340-0131
No coin nor oath required. For personal study only.
✦ Synopsis
Twenty glass industry workers from three plants exposed to different atmospheric HF-levels have been studied with respect to their renal fluoride excretion Analyses have been carried out on preshift and post-shift urine samples as well as on 24-hour urine In addition, the fluoride concentration of the working atmosphere has been determined Intake excretion balances showed that the total renal fluoride excretion was between 10 and 60 % of the inhaled HF The results lead to the conclusions:
1 There exists a direct correlation between atmospheric fluoride concentration and renal fluoride excretion (r = 0,8615).
2 There exists a significant correlation between total daily elimination of fluoride and the fluoride concentration in post-shift urine-samples (r = 0,9324).
3 As the atmospheric HF-concentration increases there appears to be a decrease in the amount of fluoride renally eliminated.
4 There is no evidence for a statistical relationship between urine fluoride concentration and long term exposure.
5 Urine fluoride analyses of post-shift samples present a suitable monitoring method for persons exposed to HF An assessment of a dose and response relationship is dependent upon the knowledge of the specific exposure at the working place The physical and chemical state of the inhalation noxious (e g gaseous HF or fluoride containing dust) ist important Thus the results from studies in the aluminium-industry (dust) cannot be compared with those obtained in the glass industry (gaseous HF).