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Renal failure and platinum pharmacokinetics in three patients treated with cis-diamminedichloroplatinum(II) and whole-body hyperthermia

โœ Scribed by Henry Gerad; Merrill J. Egorin; Margaret Whitacre; David A. Echo; Joseph Aisner

Publisher
Springer
Year
1983
Tongue
English
Weight
512 KB
Volume
11
Category
Article
ISSN
0344-5704

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We attempted to ascertain renal, hematologic, and neurologic tolerance to ifosfamide (IFX) in pediatric patients previously treated with large single and cumulative doses of cis-Diamminedichloroplatinum-ll (CDP) for osteosarcoma (0s). Twenty 0 s patients were treated with CDP: initially 150 mgh'was