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Renal Excretion of Purine Bases

✍ Scribed by Yamamoto, Tetsuya; Moriwaki, Yuji; Takahashi, Sumio; Hada, Toshikazu; Higashino, Kazuya


Book ID
119985034
Publisher
S. Karger AG
Year
1988
Tongue
English
Weight
738 KB
Volume
48
Category
Article
ISSN
0028-2766

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Wild type and mutant strains of Neurospora crassa excrete hypoxanthine, xanthine, and uric acid, but not adenine or inosine, when exogenous adenine is added to growing cultures. No detectable excretion occurs in the absence of adenine. The de novo pathway of purine biosynthesis was found to influenc