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Renal carcinoma cells undergo apoptosis without oligonucleosomal DNA fragmentation

✍ Scribed by Kenya Yamaguchi; Robert Uzzo; Nickolai Dulin; James H Finke; Vladimir Kolenko

Book ID
116288388
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
218 KB
Volume
318
Category
Article
ISSN
0006-291X

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## Abstract In order to evaluate the reliability of fibroblasts as a cell model for studying apoptosis, we tested the response of normal human fibroblasts to the oxidative stress inducers H~2~O~2~ and 2‐deoxy‐D‐ribose (dRib). Our results showed that fibroblasts treated with dRib and H~2~O~2~ are in