Renal blood flow in isolated kidneys measured with an electromagnetic flowmeter and by xenon-133 and krypton-85 wash-out techniques

✍ Scribed by J. Ladefoged; F. Pedersen; E. Bassenge; R. Rohde; U. Doutheil

• Publisher: Springer
• Year: 1968
• Tongue: English
• Weight: 416 KB
• Volume: 299
• Category: Article
• ISSN: 0031-6768
• DOI: 10.1007/bf00362539

✦ Synopsis

By use of an electromagnetic flowmeter and the inert gas desaturation method 43 comparative measurements of the blood flow were performed in 6 isolated dog kidneys. For the measurements by use of the latter method krypton-85 and xenon-133 were employed, for a fast, and respectively, a slow injection of the indicator into the renal artery. Calculation of the blood flow from the wash-out curves was made by use of the formulas advanced by KETY (1951) and by ZIV.RLE~ (1965).

A good accordance was found between the flowmeter values and those obtained with the desaturation methods. Recirculation and resorption of indicator in fat tissue surrounding the kidney explain that previous examinations in kidneys in situ have resulted in very low perfusion values, when Zierler's formula has been applied. Extrapolation of the final slope to obtain the area of the curve may be a major source of error by calculation of the blood flow with Zierler's formula.