Removal of Cellular-Type Hemoglobin-Based Oxygen Carrier (Hemoglobin-Vesicles) From Blood Using Centrifugation and Ultrafiltration

Influence of hemoglobin vesicles, cellul

Influence of hemoglobin vesicles, cellular-type artificial oxygen carriers, on human umbilical cord blood hematopoietic progenitor cells in vitro

✍ Miki Yamaguchi; Mitsuhiro Fujihara; Shinobu Wakamoto; Hiromi Sakai; Shinji Takeo 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 730 KB

## Abstract Hemoglobin vesicles (HbVs), liposomal oxygen carriers containing human hemoglobin, are candidates for development as clinically useful blood substitutes. Although HbVs are shown to distribute transiently into the bone marrow in animal models, the influence of HbVs on human hematopoietic