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Remote-Controlled System for the Production of [1-11C] Palmitic Acid

✍ Scribed by P. Goethals; G. Slegers

Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
180 KB
Volume
95
Category
Article
ISSN
0037-9646

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✦ Synopsis

A

of [l-1 with bolism semi-automated production unit is developed for the routine production .lC] palmitic acid via carbonation of n-pentadecyl magnesium bromide 'C02. The labeled compound is synthesized to study the myocardial metaby means of positron emission tomography. Chemical, radiochemical and pharmaceutical control showed that the product is suitable for human i.v. administration. In 35 min 40 to 60 mCi of [l-l'C] palmitic acid are produced in a final isotonic solution of 12 ml.

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