Remote asymmetric induction for chiral 1,4-diols using a chiral acetal derived from chiral hydrobenzoin
โ Scribed by Hiromichi Fujioka; Hidetoshi Kitagawa; Naoki Matsunaga; Yasushi Nagatomi; Yasuyuki Kita
- Book ID
- 103410097
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 241 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
Lithiated N-substituted 1,2,4-triazoles 3 and 8 and benzimidazole 11 reacted with (1R)-fenchone to give derivatives 5c, 9 and 12 in good yields as single diastereoisomers. (S)-Lactic acid 16 reacted with o-phenylenediamine 15 to give optically pure (53-2-(1-hydroxyethyl)benzimidazole 17 (85%). Ring
New exwnpZes of the cyanation reaction are described, including one that affords the cyanokydrin 8\_, an intermediate for synthesizing pyretkroid insecticides. Also the reaction with acetals derived from S-1,3-butanediol has been examined. \_ Recently we have shown that the Lewis acid catalyzed reac