✦ LIBER ✦

Remission of Non-insulin-dependent Diabetes Mellitus Following Resection of a Parathyroid Adenoma

✍ Scribed by Quin, J.D.; Gumpert, J.R.W.

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 100 KB
Volume: 14
Category: Article
ISSN: 0742-3071
DOI: 10.1002/(sici)1096-9136(199701)14:1<80::aid-dia285>3.0.co;2-w

No coin nor oath required. For personal study only.

✦ Synopsis

A 56-year-old woman presented with diabetes mellitus and primary hyperparathyroidism simultaneously. Initial random blood glucose was recorded at 20.8 mmol l -1 , serum calcium was 3.07 mmol l -1 (normal range 2.10-2.55 mmol l -1 ), and plasma parathyroid hormone estimation by intact assay was 110 ng l -1 (normal range 10-65 ng l -1 ). Initial glycated haemoglobin was 9.4 % (non-diabetic range Ͻ 7.5 %). Left lower parathyroidectomy was carried out and pathology confirmed the presence of a chief cell adenoma. The gland measured 10 × 5 × 5 mm. Following parathyroidectomy serum calcium normalized, glucose tolerance improved, and a subsequent 75 g oral glucose tolerance test was normal. The patient weighed 80 kg at presentation but the post-operative weight had risen to 81.5 kg. The most recent glycated haemoglobin was 4.6 %. Primary hyperparathyroidism may have a reversible effect on glucose tolerance.

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