✦ LIBER ✦

Remission of myasthenia gravis caused by proteinuria in nephrotic syndrome

✍ Scribed by Malaz Almsaddi; Tulio E. Bertorini; William Bastnagel

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 30 KB
Volume: 20
Category: Article
ISSN: 0148-639X
DOI: 10.1002/(sici)1097-4598(199712)20:12<1583::aid-mus14>3.0.co;2-1

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✦ Synopsis

Myasthenia gravis is caused by antibodies against acetylcholine receptors and is treated with inhibition or elimination of antibody production. We report a 43-year-old myasthenic female who was symptomatic until she developed proteinuria from nephrotic syndrome, which caused a marked drop in acetylcholine receptor antibody titer with remission of myasthenia. Treatment of the nephrotic syndrome produced exacerbation of her myasthenia and a rise in antibody level. This patient's improvement is the result of antibody elimination during proteinuria in nephrotic syndrome.