Remarkably efficient deprotection of cyclic acetals and ketals
✍ Scribed by Ali Ates; Arnaud Gautier; Bernard Leroy; Jean-Marc Plancher; Yannick Quesnel; István E Markó
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 228 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
A simple and mild procedure for the efficient deprotection of cyclic acetals and ketals, using cerium ammonium nitrate (CAN) is reported. The method tolerates a range of functional and protecting groups and is suitable for acid-labile substrates.
📜 SIMILAR VOLUMES
A novel type of photodeprotection reaction of simple aromatic acetals and ketals is described. The deprotection is highly efficient under optimized conditions. The aromatic ring confers the photoreactivity to the compounds. The efficiency of the process depends on the structure of the acetal moiety.
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