The novel solution-phase synthesis of an array of biologically relevant benzimidazoles in a simple two-step procedure is revealed. Transformations are carried out in excellent yield by condensation of mono-Boc protected ortho-phenylene diamine and supporting Ugi reagents. Subsequent acid treatment a
Remarkable three-step-one-pot solution phase preparation of novel imidazolines utilizing a UDC (Ugi/de-Boc/cyclize) strategy
β Scribed by Christopher Hulme; Liang Ma; Joseph Romano; Matthew Morrissette
- Book ID
- 104262359
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 255 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
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The novel solution-phase synthesis of an array of biologically relevant quinoxalinones in a simple two-step procedure is revealed. Transformations are carried out in excellent yield by condensation of mono-Boc protected ortho-phenylene di-amine, glyoxylic acids and supporting Ugi reagents. Subsequen
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