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Remarkable Stability of Hairpins Containing 2‘,5‘-Linked RNA Loops

✍ Scribed by Hannoush, Rami N.; Damha, Masad J.


Book ID
127122795
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
255 KB
Volume
123
Category
Article
ISSN
0002-7863

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The stability of RNA hairpin loops conta
✍ Eric Wickstrom; Ignacio Tinoco Jr. 📂 Article 📅 1974 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 875 KB

RNA oligomers with the sequence AJJ-G-Urn, n = 7-9, m = 5-10, have been synthesized and found to form hairpin loops in 21 mM or 101 mM Na+. The hairpin loops displayed melting temperatures 13'-29'C greater than that of the hairpin loop AsCs-U6 in the same solvent. The increased stability of these ha