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Remarkable reduction in acetylcholine concentration in the cerebrospinal fluid from patients with Alzheimer type dementia

✍ Scribed by Tohgi, Hideo; Abe, Takashi; Hashiguchi, Kusuo; Saheki, Mika; Takahashi, Satoshi

Book ID
121957044
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
340 KB
Volume
177
Category
Article
ISSN
0304-3940

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✍ Takashi Abe; Hideo Tohgi; Chiaki Isobe; Takahiko Murata; Chigumi Sato πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 76 KB πŸ‘ 1 views

## Abstract To investigate the possible role of oxidative RNA damage in the pathogenesis of Alzheimer's disease (AD), the concentrations of the oxidative stress marker 8‐hydroxyguanosine (8‐OHG) were measured in the cerebrospinal fluid (CSF) and the serum of patients with AD and control subjects. T