## Abstract In Huntington's disease (HD) patients, gait is characterized by a timing disorder with marked intraindividual variability in temporal gait parameters (caused by the presence of both hyperkinetic and hypokinetic features). We sought to determine the influence of use of a metronome on gai
Reliability of spatiotemporal gait outcome measures in Huntington's disease
β Scribed by Ashwini K. Rao; Lori Quinn; Karen S. Marder
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 67 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Gait impairments are very important in Huntington's disease (HD), because loss of independence in gait is an important predictor of nursing home placement. Given this importance, it is imperative to test reliable and sensitive outcome measures that can be tested easily in various clinical environments. Here, we examined the testβretest reliability of gait outcome measures using the GAITRite instrumented carpet. We tested 12 subjects with HD and 12 ageβmatched controls in two separate sessions. At each session, subjects walked across the GAITRite carpet at a comfortable speed. We used the intraclass correlation coefficient (ICC) and coefficient of variation (CoV) to measure testβretest reliability. Reliability was very high for all outcome measures (velocity, cycle time, stride length, cadence, and base of support), as seen by high ICC scores (0.86 to 0.95) and low CoV scores (0.042β0.102). In addition, the performance across the two subject groups was very different, indicating that the GAITRite is sensitive enough to distinguish between populations. Given that the GAITRite is a relatively inexpensive and portable piece of equipment, it can be used in a wide variety of clinical settings and clinical trials. Our data on high testβretest reliability and sensitivity extends the utility of the GAITRite to the HD population. Β© 2005 Movement Disorder Society
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