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Reliability of four methods for the diagnosis of acute infection by Epstein-Barr virus

✍ Scribed by J. Gutiérrez; M. Rodríguez; C. Maroto; G. Piédrola

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
24 KB
Volume
11
Category
Article
ISSN
0887-8013

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✦ Synopsis

We studied the reliability of new indirect tests in the diagnosis of acute infection by Epstein-Barr virus (EBV). Studied for all samples were: method 1, the heterophil antibodies (Abs) (Monolatex, Biokit, Germany); method 2, the IgM Abs to EBV with ELISA tests (antigen pools, Enzygnost, Behringwerke, Germany); method 3, EA (Biotest Diagnostics, Germany); and method 4, the IgG avidity test. The reliability of the four tests for the detection of primary infection by EBV was: sensitivity (method 1: 89.1%; method 2: 100%; method 3: 79.7%; method 4: 99%); specificity (method 1: 98%; method 2: 100%; method 3: 84%; method 4: 100%); positive predictive value (method 1: 97

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