The response surface method incorporating multivariate spline interpolation (RSM-S) is a powerful technique for the formulation optimization of pharmaceuticals. However, no satisfactory method has been developed to evaluate the reliability of the optimal solution. We integrated bootstrap (BS) resamp
✦ LIBER ✦
Reliability evaluation of nonlinear design space in pharmaceutical product development
✍ Scribed by Yoshihiro Hayashi; Shingo Kikuchi; Yoshinori Onuki; Kozo Takayama
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 443 KB
- Volume
- 101
- Category
- Article
- ISSN
- 0022-3549
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