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Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells

✍ Scribed by Matthew S. Squires; E.Ann Hudson; Lynne Howells; Stewart Sale; Catherine E. Houghton; J.Louise Jones; Louise H. Fox; Martin Dickens; Sally A. Prigent; Margaret M. Manson


Book ID
113993332
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
668 KB
Volume
65
Category
Article
ISSN
0006-2952

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Mitogen-activated protein kinases (MAPKs) play a major role in the mitogenic signal transduction pathway and are essential components of both growth and differentiation. Constitutive activation of the MAPK cascade is associated with the carcinogenesis and metastasis of human breast and renal cell ca