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Relevance of BCAR4 in tamoxifen resistance and tumour aggressiveness of human breast cancer

โœ Scribed by Godinho, M F E; Sieuwerts, A M; Look, M P; Meijer, D; Foekens, J A; Dorssers, L C J; van Agthoven, T


Book ID
110000668
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
515 KB
Volume
103
Category
Article
ISSN
0007-0920

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Characterization of BCAR4, a novel oncog
โœ Marcia Godinho; Danielle Meijer; Buddy Setyono-Han; Lambert C.J. Dorssers; Ton v ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 406 KB

Resistance to the antiestrogen tamoxifen remains a major problem in the management of estrogen receptor-positive breast cancer. Knowledge on the resistance mechanisms is needed to develop more effective therapies. Breast cancer antiestrogen resistance 4 (BCAR4) was identified in a functional screen