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Release of urokinase plasminogen activator receptor during urosepsis and endotoxemia

✍ Scribed by Rondeau, Eric

Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
40 KB
Volume
61
Category
Article
ISSN
0085-2538

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The generation of the broad specificity serine protease plasmin in the pericellular environment is regulated by binding of the urokinase-type plasminogen activator (uPA) to its specific glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor, uPAR. This interaction potentiates the reciproc