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Release of Bioactive Transforming Growth Factor β 3 from Microtextured Polymer Surfaces in Vitro and in Vivo

✍ Scribed by Parker, J.A.T.C.; Brunner, G.; Walboomers, X.F.; Von den Hoff, J.W.; Maltha, J.C.; Jansen, J.A.

Book ID: 118132948
Publisher: Mary Ann Liebert
Year: 2002
Tongue: English
Weight: 214 KB
Volume: 8
Category: Article
ISSN: 1076-3279
DOI: 10.1089/10763270260424213

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## Abstract Regeneration of peripheral nerves after injury is suboptimal. We now report the long term delivery of nerve growth factor (NGF) by biodegradable poly‐lactic‐__co__‐glycolic acid (PLGA) microspheres __in vitro__ and __in vivo__. Lactic to glycolic acid ratios of 50:50 and 85:15 were fabr