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Release of ATP from cultured rat astrocytes elicited by glutamate receptor activation

✍ Scribed by G Queiroz; P.J Gebicke-Haerter; A Schobert; K Starke; I von Kügelgen


Book ID
117491700
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
223 KB
Volume
78
Category
Article
ISSN
0306-4522

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## Abstract Nitric oxide (NO; 1 μM) or an NO donor (500 μM diethylenetriamine‐nitric oxide, DETA‐NONOate) caused rapid glutamate and ATP release from cultured rat cortical astrocytes. NO‐induced glutamate release was prevented by calcium chelators (EGTA or BAPTA‐AM) and an inhibitor of vesicular ex