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Release and activity of anti-TNFα therapeutics from injectable chitosan preparations for local drug delivery

✍ Scribed by Mohammed F. Shamji; Priscilla Hwang; Robert W. Bullock; Samuel B. Adams; Dana L. Nettles; Lori A. Setton


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
31 KB
Volume
92B
Category
Article
ISSN
1552-4973

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Release and activity of anti-TNFα therap
✍ Mohammed F. Shamji; Priscilla Hwang; Robert W. Bullock; Samuel B. Adams; Dana L. 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 252 KB

## Abstract __Background:__ Tumor necrosis factor alpha (TNFα) is a cytokine that regulates immune and inflammatory overactivation in various pathological states. Protein therapeutics may antagonize this cytokine, but may also have systemic toxicities. Small molecule natural products are also effic