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Relaxin Modulates Collagen Type I and Matrix Metalloproteinase-1 Expression by Human Periodontal Ligament Cells

✍ Scribed by Takano, Machi; Yamaguchi, Masaru; Nakajima, Ryo; Kojima, Tadashi; Kasai, Kazutaka

Book ID: 123449052
Publisher: Japan Science and Technology Information Aggregator, Electronic
Year: 2008
Tongue: English
Weight: 233 KB
Volume: 50
Category: Article
ISSN: 1349-0079
DOI: 10.1016/S1349-0079(08)80011-4

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## Abstract Type I collagen (COL I) is the predominant collagen in the extracellular matrix of periodontal ligament (PDL), and its expression in PDL fibroblasts (PLF) is sensitive to mechanical force. However, the mechanism by which PLF induces COL I to respond to mechanical force is unclear. This