Relaxation of vascular smooth muscle by the cGMP-kinase substrate IRAG
โ Scribed by Dominik Bernhard; Franz Hofmann; Jens Schlossmann
- Publisher
- BioMed Central
- Year
- 2007
- Tongue
- English
- Weight
- 191 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1471-2210
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
We tested the hypothesis that Mg 2รพ influences growth of vascular smooth muscle cells (VSMCs) by modulating cell cycle activation through mitogen-activated protein (MAP) kinase-dependent pathways. Rat VSMCs were grown in culture medium containing normal Mg 2รพ (1.02 mmol/L, control) and increasing co
Heparin and heparan are potent inhibitors of vascular smooth muscle cell (VSMC) proliferation. To investigate the mechanisms by which heparin suppresses growth factor stimulated mitogenesis, the present experiments investigated the effects of heparin on platelet-derived growth factor (PDGF) stimulat
## Abstract In certain cell systems, including neonatal vascular smooth muscle (VSM) cells, phorbol esters are growth inhibitory. Here we show that 1, 2โdioctanoylโsnglycerol (DiC8), when added 2 h after ฮฑโthrombin, reverses by 95% the induction of DNA synthesis in VSM cells by ฮฑโthrombin. Sphingos