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Relaxant effects of BRL 38227 and pinacidil on the rat gastric fundus

โœ Scribed by Romain A. Lefebvre; Jiri Horacek


Book ID
115887416
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
493 KB
Volume
214
Category
Article
ISSN
0014-2999

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Relaxant Effects of the Potassium Channe
โœ D.R. Buckle; J.R.S. Arch; N.E. Bowring; K.A. Foster; J.F. Taylor; S.G. Taylor; D ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Elsevier ๐ŸŒ English โš– 525 KB

SUMMARY: The airways relaxant effects and mechanism of action of the potassium channel activators BRL 38227 and pinacidil have been compared in guinea-pig and human airways. BRL 38227 was a potent relaxant in guinea-pig isolated trachealis ( \(\mathrm{IC}_{50}=4.9 \times 10^{-7} \mathrm{M}\) against