Relaxant Effects of the Potassium Channe
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D.R. Buckle; J.R.S. Arch; N.E. Bowring; K.A. Foster; J.F. Taylor; S.G. Taylor; D
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Article
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1993
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Elsevier
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English
โ 525 KB
SUMMARY: The airways relaxant effects and mechanism of action of the potassium channel activators BRL 38227 and pinacidil have been compared in guinea-pig and human airways. BRL 38227 was a potent relaxant in guinea-pig isolated trachealis ( \(\mathrm{IC}_{50}=4.9 \times 10^{-7} \mathrm{M}\) against