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Relative roles of TGF-β1 and Wnt in the systemic regulation and aging of satellite cell responses

✍ Scribed by Morgan E. Carlson; Michael J. Conboy; Michael Hsu; Laurel Barchas; Jaemin Jeong; Anshu Agrawal; Amanda J. Mikels; Smita Agrawal; David V. Schaffer; Irina M. Conboy

Book ID
111199582
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
919 KB
Volume
8
Category
Article
ISSN
1474-9718

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## Abstract To better understand the complex roles of transforming growth factor‐beta (TGF‐β) in bone metabolism, we examined the impact of a range of TGF‐β concentrations on osteoclast differentiation. In co‐cultures of support cells and spleen or marrow osteoclast precursors, low TGF‐β concentrat