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Relative rates of insertion and deletion mutations in a microsatellite sequence in cultured cells

โœ Scribed by Twerdi, C. D.; Boyer, J. C.; Farber, R. A.


Book ID
121751390
Publisher
National Academy of Sciences
Year
1999
Tongue
English
Weight
93 KB
Volume
96
Category
Article
ISSN
0027-8424

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Acultured mouse cell line with an integrated copy of a plasmid that contains a short dinucleotide repeat sequence (microsatellite) has been used to determine the frequencies and types of mutation induced by two frameshih mutagens. The presence of the microsatellite, which consists of 17 repeats of a