𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Relative position of trypsin banded homologous chromosomes in human (♀) metaphase figures

✍ Scribed by Luc Hens; M. Kirsch-Volders; Charles Susanne; H. Galperin-Lemaître


Publisher
Springer
Year
1975
Tongue
English
Weight
425 KB
Volume
28
Category
Article
ISSN
0340-6717

No coin nor oath required. For personal study only.

✦ Synopsis


"Generalized distances" between centromeres were statistically analyzed (chi2 test) on 50 normal female trypsin-banded metaphase figures. This study revealed that the homologous chromosomes of the pairs 13, 17, 14, and 21 lie closer together than would be expected by a reference distribution, and this in a statistically significant way. The same relative position was demonstrated for the chromosome groups 13-14, 13-21, 14-21, 15-22, and 14-22. Evidences were collected that also showed that homologous chromosomes of the pairs 1, 19, and 20 and the chromosome groups 15-21, 13-15, and 18-20 tend to lie closer together. Giving a functional interpretation to the phenomenon of non-random distribution of chromosomes in metaphase figures, it may be suggested that the chromosomes 13, 14, and 21 are involved in the organization of the human nucleolar organizers, more frequently than the other D- and G-group chromosomes.


📜 SIMILAR VOLUMES


The differential distribution of X-ray i
✍ Patricia Cooke; Marina Seabright; Margaret Wheeler 📂 Article 📅 1975 🏛 Springer 🌐 English ⚖ 485 KB

The distribution of X-ray induced aberrations between trypsin-banded regions within human chromosomes has been studied in over a thousand cells from normal and abnormal individuals. An analysis of this data has been performed for each type of aberration separately, taking into account the relative a

Number and localization of sets of homol
✍ M. G. Neijzing 📂 Article 📅 1985 🏛 Springer Netherlands 🌐 English ⚖ 690 KB

In a previous paper it was shown that chiasmata are involved in the metaphase-I associations of haploid rye. Ring univalents and associations of two and more chromosomes were assumed to be formed by chiasma formation in several sets of homologous segments. An attempt is made to deduce the number of