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Relative immunosuppressive potency of various corticosteroids measured in vitro

โœ Scribed by E. Langhoff; J. Ladefoged

Book ID
104798037
Publisher
Springer
Year
1983
Tongue
English
Weight
389 KB
Volume
25
Category
Article
ISSN
0031-6970

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Relative immunosuppressive potency of th
Relative immunosuppressive potency of therapeutic corticosteroids measured by whole blood lymphocyte proliferation
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The in vitro immunosuppressive potency of several therapeutic corticosteroids was investigated using a whole-blood lymphocyte proliferation assay. The selected steroids included beclomethasone dipropionate (BDP), betamethasone (BET), budesonide (BUD), dexamethasone (DEX), flunisolide (FLU), fluticas

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The penetration through the epidermis in vitro of various topically used corticosteroids was compared. The amount penetrating through the epidermis from an ethanolic solution showed good correlation with the polarity of the eorticosteroids under study. Hydrocortisone, the mos t polar corticosteroid,