Relative Flexibility of DNA and RNA: a Molecular Dynamics Study
✍ Scribed by Agnes Noy; Alberto Pérez; Filip Lankas; F. Javier Luque; Modesto Orozco
- Book ID
- 116661511
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 595 KB
- Volume
- 343
- Category
- Article
- ISSN
- 0022-2836
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## Abstract Recent studies of DNA axis curvature and flexibility based on molecular dynamics (MD) simulations on DNA are reviewed. The MD simulations are on DNA sequences up to 25 base pairs in length, including explicit consideration of counterions and waters in the computational model. MD studies
In this exploratory study, the methods of molecular dynamics and Brownian dynamics have been used to investigate the dynamics of ring formation in a simple, idealised, flexible molecule. Particular attention has been paid to the formation and persistence of the bond responsible for ring closure. The