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Relationships between lifestyle factors and neutrophil functions in the elderly

โœ Scribed by Kazumasa Tsukamoto; Katsuhiko Suzuki; Kazuhiko Machida; Chinatsu Saiki; Rumiko Murayama; Minoru Sugita

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
107 KB
Volume
16
Category
Article
ISSN
0887-8013

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โœฆ Synopsis

Abstract

We investigated the relationships between neutrophil functions and lifestyle factors in the elderly. The subjects (84 males, 73.9ยฑ5.8 years old; and 63 females, 70.0ยฑ4.6 years old) belonged to a recreational seniors club in Japan. Investigations of the subjects' stress, exercise habits, smoking habits, and alcoholโ€drinking habits were performed. The phagocytosis and superoxide productivity of the neutrophils were measured with a nitroblue tetrazolium (NBT) reduction test. In addition, leukocyte counts and serum total protein (TP) levels were determined. The results revealed that aging, high serum levels, and stressโ€coping factors (e.g., having hobbies, keeping pets, and close links with friends or family) significantly correlated with preferable neutrophil functions. In addition, significant effects of lifestyle factors on the balance between phagocytosis and subsequent superoxide production were observed. Thus, the results of the present study suggest that there are correlations between neutrophil functions and lifestyle factors in the elderly. J. Clin. Lab. Anal. 16:266โ€“272, 2002. ยฉ 2002 Wileyโ€Liss, Inc.

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