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Relationships between Hippocampal Atrophy, White Matter Disruption, and Gray Matter Hypometabolism in Alzheimer's Disease

✍ Scribed by Villain, N.; Desgranges, B.; Viader, F.; de la Sayette, V.; Mezenge, F.; Landeau, B.; Baron, J.-C.; Eustache, F.; Chetelat, G.

Book ID
120392297
Publisher
Society for Neuroscience
Year
2008
Tongue
English
Weight
400 KB
Volume
28
Category
Article
ISSN
0270-6474

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## Abstract The relationship between the extent of local gray/white matter atrophy, genetic load, and clinical impairment was studied in Huntington's disease (HD) by means of voxel‐based morphometry. T1‐weighted brain images from 33 patients (mean age 49.5, range 25–73 years) with HD duration of 1