Relationships Between Bone Mineral Density and Incident Vertebral Fracture Risk with Raloxifene Therapy
β Scribed by Somnath Sarkar; Bruce H. Mitlak; Mayme Wong; John L. Stock; Dennis M. Black; Kristine D. Harper
- Book ID
- 111487030
- Publisher
- American Society for Bone and Mineral Research
- Year
- 2002
- Tongue
- English
- Weight
- 423 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0884-0431
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π SIMILAR VOLUMES
Dual-energy X-ray absorptiometric bone mineral density (DXA BMD) is a strong predictor of fracture risk in untreated patients. However, previous patient-level studies suggest that BMD changes explain little of the fracture risk reduction observed with osteoporosis treatment. We investigated the rele
## Abstract Surrogate markers of fracture riskβbone turnover markers (BTMs) and bone mineral density (BMD)βcan be used to monitor treatment response. We assessed whether changes in these markers greater than the least significant change (LSC) were associated with fracture risk reduction and greater