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Relationship of the CYNAP phenomenon and antiglobulin-augmented lymphocytotoxicity

✍ Scribed by Phelan, D.; Gebel, H.; Fuller, T.; Rodey, G.

Book ID
121779919
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
57 KB
Volume
1
Category
Article
ISSN
0198-8859

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To investigate the interaction of folate deficiency and alkylating agents in vivo, weanling Fischer 344 rats were maintained for 5 weeks on a folate replete, moderately folate deficient, or a severely folate deficient diet. Mutant frequencies at the HPRT locus in splenic lymphocytes were 1.2+/-0.6,