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Relationship of serum methotrexate concentration in high-dose methotrexate chemotherapy to prognosis and tolerability: A prospective cohort study in chinese adults with osteosarcoma

โœ Scribed by Feng Lin; Yue Juan; Shui-Er Zheng; Zan Shen; Li-Na Tang; Hui Zhao; Yang Yao


Book ID
116396358
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
120 KB
Volume
70
Category
Article
ISSN
0011-393X

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A randomized study comparing high-dose m
โœ Krailo, M. ;Ertel, I. ;Makley, J. ;Fryer, C. J. H. ;Baum, E. ;Weetman, R. ;Yunis ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 591 KB

Methotrexate (MTX) has demonstrated significant activity against relapsed and metastatic osteosarcoma. However, there is little published data to indicate the appropriate dose for MTX when given as a component of a multidrug regimen for the treatment of osteosarcoma. Therefore, the investigators at