A randomized study comparing high-dose m
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Krailo, M. ;Ertel, I. ;Makley, J. ;Fryer, C. J. H. ;Baum, E. ;Weetman, R. ;Yunis
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Article
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1987
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John Wiley and Sons
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English
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Methotrexate (MTX) has demonstrated significant activity against relapsed and metastatic osteosarcoma. However, there is little published data to indicate the appropriate dose for MTX when given as a component of a multidrug regimen for the treatment of osteosarcoma. Therefore, the investigators at