Relationship of pre-S encoded antigens in liver and clinical manifestations of chronic hepatitis B infection
✍ Scribed by G. Hess; W. H. Gerlich; G. Gerken; M. Manns; K.-H. Meyer zum Büschenfelde
- Book ID
- 114796559
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 475 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0106-9543
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📜 SIMILAR VOLUMES
The serum kinetics of preS 1 and preS2 antigens has been evaluated in 38 serial samples from eight patients with chronic active (CAH) or chronic persistent (CPH) hepatitis, followed for 2-7 years (mean 4.4 years) in whom liver biopsy was performed at intervals, and in 46 samples from ten asymptomati
## Abstract Frozen cryostat sections and sera from 30 patients with chronic delta infection were examined for pre‐S1 and pre‐S2 gene‐encoded proteins, and the results were compared to markers in liver and serum HBV and HDV replication. Pre‐S1 and pre‐S2 were detected by indirect immunofluorescence
The large (pre-S1), middle (pre-S2) and major (P24) polypeptides of HBsAg have been defined in detail, but their role in hepatitis B virus infection is not known. Therefore, we studied the expression of pre-S1, pre-S2 and P24 in the liver of 15 patients with acute or chronic hepatitis B virus infect