Relationship of internal cyclic AMP levels, rates of protein synthesis and mucor dimorphism

✍ Scribed by Michael Orlowski; Joseph F. Ross

• Book ID: 104760673
• Publisher: Springer
• Year: 1981
• Tongue: English
• Weight: 448 KB
• Volume: 129
• Category: Article
• ISSN: 0302-8933
• DOI: 10.1007/bf00406461

✦ Synopsis

Changes in the intracellular pools of cyclic AMP and specific rates of protein synthesis have been described as correlates of the yeast-to-hypha conversion in Mucor racemosis. A further examination of the relationship between these physiological parameters and the cellular morphogenesis was conducted in the present study. The levels of intracellular cyclic AMP consistently varied as a function of the cell morphology rather than the CO2 tension, oxygen tension or growth rate. The specific rate of protein synthesis failed to change during a N2-to-air-induced yeast-to-hypha transition. Previously reported changes in this parameter during CO2-to-air-and CO2-to-N2-induced yeast-to-hypha shifts may be a consequence of growth rate changes rather than development per se,