Examination of p53 alterations and cytok
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Marshall Anderson; Sue Sladon; Ruth Michels; Lois Davidson; Kenneth Conwell II;
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Article
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1996
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John Wiley and Sons
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English
⚖ 545 KB
Mutations in the p53 gene are detected in greater than 50% of squamous cell carcinomas of the lung and to a lesser extent in adenocarcinomas. The p53 protein is also overexpressed in a relatively high percentage of preinvasive lesions of the bronchial epithelium. However, unlike tumor tissue, immuno