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Relationship of immunohistochemistry scores of altered p53 protein expression in relation to patient’s habits and histological grades and stages of squamous cell carcinoma

✍ Scribed by Mulazim H. Bukhari; Shahida Niazi; Naseer A. Chaudhry


Book ID
111242397
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
607 KB
Volume
36
Category
Article
ISSN
0303-6987

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Examination of p53 alterations and cytok
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Mutations in the p53 gene are detected in greater than 50% of squamous cell carcinomas of the lung and to a lesser extent in adenocarcinomas. The p53 protein is also overexpressed in a relatively high percentage of preinvasive lesions of the bronchial epithelium. However, unlike tumor tissue, immuno