## Abstract A preliminary investigation was carried out to determine how conditional lethal mutants affected in particular aminoacyl‐tRNA synthetases may be used to study the role of tRNA charging levels in protein synthesis. The relationship between rate of protein synthesis and level of histidyl‐
✦ LIBER ✦
Relationship of differential proteoglycan biosynthesis in wild type and mutant chinese hamster ovary cell lines to levels of hypoxia in vivo
✍ Scribed by John T. Leith
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 263 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0360-3016
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The production of Chinese hamster ovary (CHO) cell mutants which are defective in endocytosis has led to a greater understanding of the process by which cells sort ligands and their receptors. Robbins and coworkers have obtained CHO mutants which are resistant to diphtheria toxin, defective in the d