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Relationship of asymmetric dimethylarginine to haemodialysis hypotension

✍ Scribed by Stefania Bergamini; Lorenza Vandelli; Elisa Bellei; Cristina Rota; Paolo Manfredini; Aldo Tomasi; Alberto Albertazzi; Anna Iannone

Book ID
116789911
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
368 KB
Volume
11
Category
Article
ISSN
1089-8603

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Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of endothelial nitric oxide (NO) synthase. Its concentration is elevated in patients with end-stage renal disease (ESRD), in part because it is excreted via the kidneys. In addition, ADMA is degraded by the enzyme dimethylarginine dimethy

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## Abstract ## Objective Systemic lupus erythematosus (SLE) is independently associated with accelerated atherosclerosis and premature arterial stiffening. Asymmetric dimethylarginine (ADMA) and homocysteine are mechanistically interrelated mediators of endothelial dysfunction and correlates of at