Relationship between3H-histamine uptake and H2-receptors in the human promyelocytic leukemia cell line HL-60

P-glycoprotein and alterations in the gl

P-glycoprotein and alterations in the glutathione/glutathione-peroxidase cycle underlie doxorubicin resistance in HL-60-R, a subclone of the HL-60 human leukemia cell line

✍ Ganapathirama Raghu; Mario Pierre-Jerome; Margaret S. Dordal; Philip Simonian; K 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 French ⚖ 968 KB

## Abstract HL‐60‐R, a multi‐drug‐resistant (MDR) subclone of the human leukemia cell line HL‐60, was selected in continuous culture in doxorubicin (DOX) in the absence of mutagenic agents. When compared to the parent line HL‐60, HL‐60‐R showed greater relative resistance to vinblastine than to eto