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Relationship between the Pharmacokinetics of Irinotecan and Diarrhea during Combination Chemotherapy with Cisplatin

โœ Scribed by Kudoh, Shinzoh ;Fukuoka, Masahiro ;Masuda, Noriyuki ;Yoshikawa, Atsuko ;Kusunoki, Yoko ;Matsui, Kaoru ;Negoro, Shun-ichi ;Takifuji, Nobuhide ;Nakagawa, Kazuhiko ;Hirashima, Tomonori ;Yana, Takashi ;Takada, Minoru

Book ID
108581100
Publisher
Wiley (Blackwell Publishing)
Year
1995
Tongue
English
Weight
418 KB
Volume
86
Category
Article
ISSN
0910-5050

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Cisplatin in combination with irinotecan
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โœ Takashi Nakano; A. Philippe Chahinian; Miho Shinjo; Naoki Togawa; Atsushi Tonomu ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 161 KB ๐Ÿ‘ 2 views

The purpose of this study was to assess the efficacy and toxicity of a combination of cisplatin and irinotecan (CPT-11) in the treatment of patients with malignant pleural mesothelioma and to characterize the pharmacokinetic profiles of CPT-11 and its active metabolite, 7-ethyl-10-hydroxycamptotheci