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Relationship between the fatty acid composition and the type of antibiotics produced by Streptomyces lasaliensis

✍ Scribed by Dr. M. Podojil; N. Steinerová; J. Cudlín

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 288 KB
Volume: 29
Category: Article
ISSN: 0233-111X
DOI: 10.1002/jobm.3620290910

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✦ Synopsis

The GC-MS method was used to analyze fatty acids in a parent strain of Strepiomyces lasaliensis and its two mutants producing only lasalocid or quinomycin. The biosynthesis of these substances bears relation to differences in the relative proportion of fatty acids. Biosynthetic relationships were revealed between the starter fatty acid units, their precursors, i.e. valine, leucine and isoleucine, and the type of the antibiotic produced.

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