Acute versus repeated administration of
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M. Poncelet; G. Gaudel; S. Danti; Ph. SoubriΓ©; P. Simon
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Article
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1986
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Springer
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English
β 242 KB
Immobility scores in the swimming test and brain concentrations of desipramine were determined in rats and mice following repeated injection of the antidepressant versus acute administration of either a behaviorally effective or ineffective dose of the drug. Five injections (IP) of desipramine (each