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Relationship between the activation of heat shock factor and the suppression of nuclear factor-κB activity in rat hepatocyte cultures treated with cyclosporine A

✍ Scribed by David Andrés; Carmen Dı́ez-Fernández; Antonio Castrillo; Marı́a Cascales


Book ID
113993121
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
449 KB
Volume
64
Category
Article
ISSN
0006-2952

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## Rat hepatic stellate cells (HSC ) cultured in serumcontaining medium underwent a rapid (3-hour) classical induction of p50:p65 and p65:p65 nuclear factor-B (NF-B) dimers. Subsequent culturing was associated with prolonged expression of active p50:p65 and persistent induction of a high-mobility