A quantitative structure-property relationship (QSPR) was developed for predicting the aqueous solubility of drug-like compounds from their chemical structures. A set of 321 structurally diverse drugs or related compounds, with their intrinsic aqueous solubility collected from literature, was used i
โฆ LIBER โฆ
Relationship between Structure and Solubility of Organic Lithium Compounds
โ Scribed by Kamienski, Conrad W.; Lewis, Dennis H.
- Book ID
- 121506307
- Publisher
- American Chemical Society
- Year
- 1965
- Tongue
- English
- Weight
- 934 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
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## A significant correlation was found between half-wave potentials of organic compounds and their topological indices, Axlr Ax2, and A,,. The simplicity of calculation of the index from the connectivity in the molecular skeleton, together with the significant correlation, indicates its practical